protein subcellular localization analysis Search Results


annotation of protein subcellular localization  (Human Protein Atlas)
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Human Protein Atlas annotation of protein subcellular localization
Annotation Of Protein Subcellular Localization, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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data pertaining to the subcellular localization of hoxb8  (Human Protein Atlas)
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Human Protein Atlas data pertaining to the subcellular localization of hoxb8
Data Pertaining To The Subcellular Localization Of Hoxb8, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human protein atlas mitochondrial sub-cellular location  (Human Protein Atlas)
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Human Protein Atlas human protein atlas mitochondrial sub-cellular location
Human Protein Atlas Mitochondrial Sub Cellular Location, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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subcellular localization of olr-1  (Human Protein Atlas)
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Human Protein Atlas subcellular localization of olr-1
Subcellular Localization Of Olr 1, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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protein subcellular localization prediction tool  (GenScript corporation)
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GenScript corporation protein subcellular localization prediction tool
Protein Subcellular Localization Prediction Tool, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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subcellular localization of ctsf  (Human Protein Atlas)
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Human Protein Atlas subcellular localization of ctsf
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Subcellular Localization Of Ctsf, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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predict subcellular localization of the identified nac family proteins using protcomp  (Softberry Inc)
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Softberry Inc predict subcellular localization of the identified nac family proteins using protcomp
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Predict Subcellular Localization Of The Identified Nac Family Proteins Using Protcomp, supplied by Softberry Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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predict subcellular localization of the identified nac family proteins using protcomp - by Bioz Stars, 2026-04
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genome-wide analysis of major subcellular localization information of human proteins based on immunofluorescent stained cells  (Human Protein Atlas)
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Human Protein Atlas genome-wide analysis of major subcellular localization information of human proteins based on immunofluorescent stained cells
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Genome Wide Analysis Of Major Subcellular Localization Information Of Human Proteins Based On Immunofluorescent Stained Cells, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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suba – subcellular localization database for proteins  (Millar Inc)
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Millar Inc suba – subcellular localization database for proteins
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Suba – Subcellular Localization Database For Proteins, supplied by Millar Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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subcellular localization of cxcr2  (Human Protein Atlas)
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Human Protein Atlas subcellular localization of cxcr2
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Subcellular Localization Of Cxcr2, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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protein subcellular localization prediction tool psort  (GenScript corporation)
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GenScript corporation protein subcellular localization prediction tool psort
<t>CTSF</t> Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); <t>E</t> <t>IHC</t> staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)
Protein Subcellular Localization Prediction Tool Psort, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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immunohistochemistry (ihc) staining and subcellular localization analysis of pus1 in hcc  (Human Protein Atlas)
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Human Protein Atlas immunohistochemistry (ihc) staining and subcellular localization analysis of pus1 in hcc
PUS1 expression increased in <t>HCC.</t> (A) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the UALCAN website. (B) The protein expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the CPTAC database in UALCAN website. (C–H) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on E-MTAB-6695, E-MTAB-4171, GSE39791, GSE47197, GSE54236, and GSE25079. (I) The protein expression of PUS1 between normal liver cell lines (LO2, WRL68) and HCC cell lines (Huh7, HepG2, SUN449, and PLC/PRF/5). (J, K) <t>The</t> <t>immunohistochemistry</t> of PUS1 in liver tissue and HCC from THE HUMAN PROTEIN ATLAS. (L, M) . The expression of PUS1 between liver tissue and HCC from 45 patients. (*P < 0.05, ***P < 0.001).
Immunohistochemistry (Ihc) Staining And Subcellular Localization Analysis Of Pus1 In Hcc, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


CTSF Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); E IHC staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)

Journal: BMC Pulmonary Medicine

Article Title: Expression signature, prognosis value and immune characteristics of cathepsin F in non-small cell lung cancer identified by bioinformatics assessment

doi: 10.1186/s12890-021-01796-w

Figure Lengend Snippet: CTSF Expression in human normal tissues and cancer samples. A CTSF expression in human normal tissues (GTEx database); B Comparison of CTSF expression between human normal tissues and cancer tissues (TIMER database); C Comparison of CTSF expression between unpaired normal lung tissues and tumor tissues of LUAD (left) and LUSC (right), respectively (TCGA database); D comparison of CTSF expression between paired tumor tissues and corresponding paracancerous tissues of LUAD (left) and LUSC (right), respectively (TCGA database); E IHC staining of CTSF in normal lung tissues and cancer samples of patients with LUAD or LUSC, respectively (THPA database); F subcellular localization of CTSF in different cell lines of human cancers (THPA database)

Article Snippet: Immunohistochemistry (IHC) staining and subcellular localization of CTSF were derived from The Human Protein Atlas (THPA) dataset ( https://www.proteinatlas.org/ENSG00000174080-CTSF/pathology/lung+cancer ).

Techniques: Expressing, Comparison, Immunohistochemistry

PUS1 expression increased in HCC. (A) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the UALCAN website. (B) The protein expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the CPTAC database in UALCAN website. (C–H) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on E-MTAB-6695, E-MTAB-4171, GSE39791, GSE47197, GSE54236, and GSE25079. (I) The protein expression of PUS1 between normal liver cell lines (LO2, WRL68) and HCC cell lines (Huh7, HepG2, SUN449, and PLC/PRF/5). (J, K) The immunohistochemistry of PUS1 in liver tissue and HCC from THE HUMAN PROTEIN ATLAS. (L, M) . The expression of PUS1 between liver tissue and HCC from 45 patients. (*P < 0.05, ***P < 0.001).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: PUS1 expression increased in HCC. (A) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the UALCAN website. (B) The protein expression of PUS1 between normal tissue and primary HCC tissue analyzed based on the CPTAC database in UALCAN website. (C–H) The mRNA expression of PUS1 between normal tissue and primary HCC tissue analyzed based on E-MTAB-6695, E-MTAB-4171, GSE39791, GSE47197, GSE54236, and GSE25079. (I) The protein expression of PUS1 between normal liver cell lines (LO2, WRL68) and HCC cell lines (Huh7, HepG2, SUN449, and PLC/PRF/5). (J, K) The immunohistochemistry of PUS1 in liver tissue and HCC from THE HUMAN PROTEIN ATLAS. (L, M) . The expression of PUS1 between liver tissue and HCC from 45 patients. (*P < 0.05, ***P < 0.001).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Expressing, Immunohistochemistry

High PUS1 expression was positively correlated with occurrence and malignant progression of HCC. (A) The expression of PUS1 stratified by normal, hepatitis, cirrhosis, and HCC based on the GSE54238. (B, C) The expression of PUS1 stratified by cirrhosis and HCC based on the GSE17548 and GSE56140. (D) The expression of PUS1 based on different stage in 45 HCC patients. (E) The expression of PUS1 in primary and metastasis tumor in 45 HCC patients. (F) The expression of PUS1 stratified by different grade in HCC based on the E-MTAB-8887. (G) The expression of PUS1 stratified by different stage in HCC based on the UALCAN website. (H) The expression of PUS1 stratified by different grade in HCC based on the UALCAN website. (*P<0.05, **P<0.01, ***P<0.001, ****P<0.0001).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: High PUS1 expression was positively correlated with occurrence and malignant progression of HCC. (A) The expression of PUS1 stratified by normal, hepatitis, cirrhosis, and HCC based on the GSE54238. (B, C) The expression of PUS1 stratified by cirrhosis and HCC based on the GSE17548 and GSE56140. (D) The expression of PUS1 based on different stage in 45 HCC patients. (E) The expression of PUS1 in primary and metastasis tumor in 45 HCC patients. (F) The expression of PUS1 stratified by different grade in HCC based on the E-MTAB-8887. (G) The expression of PUS1 stratified by different stage in HCC based on the UALCAN website. (H) The expression of PUS1 stratified by different grade in HCC based on the UALCAN website. (*P<0.05, **P<0.01, ***P<0.001, ****P<0.0001).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Expressing

High PUS1 expression in HCC predicted poor prognosis. (A–D) OS, DSS, PFS, and RFS Kaplan–Meier curves comparing the high and low expression of PUS1. (80324 is the RNA-seq ID of PUS1.).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: High PUS1 expression in HCC predicted poor prognosis. (A–D) OS, DSS, PFS, and RFS Kaplan–Meier curves comparing the high and low expression of PUS1. (80324 is the RNA-seq ID of PUS1.).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Expressing, RNA Sequencing

PUS1 silencing inhibited HCC cell proliferation and colony formation, and promoted cell apoptosis. (A) RT-PCR analysis of PUS1 expression in SNU449 cell and HepG2 (B) after transfection with control or PUS1 siRNAs. (C, D) Cell proliferation of SNU449 and HepG2 cells transfected with NC or PUS1 siRNA analyzed by MTT assay. (E, F) Knockdown of PUS1 dramatically inhibited the cell colony formation ability. (G, H) Apoptosis assay by flow cytometric analysis revealed PUS1–siRNA promoted apoptosis in SNU449 and HepG2 cells. (I) Knockdown of PUS1 hardly inhibited the cell colony formation ability of LO2 and WRL68 cells. (J, K) Knockdown of PUS1 hardly inhibited the cell proliferation of LO2 and WRL68 cells. (*P<0.05, **P<0.01, ***P<0.001, ****P<0.0001; ns, P>0.05).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: PUS1 silencing inhibited HCC cell proliferation and colony formation, and promoted cell apoptosis. (A) RT-PCR analysis of PUS1 expression in SNU449 cell and HepG2 (B) after transfection with control or PUS1 siRNAs. (C, D) Cell proliferation of SNU449 and HepG2 cells transfected with NC or PUS1 siRNA analyzed by MTT assay. (E, F) Knockdown of PUS1 dramatically inhibited the cell colony formation ability. (G, H) Apoptosis assay by flow cytometric analysis revealed PUS1–siRNA promoted apoptosis in SNU449 and HepG2 cells. (I) Knockdown of PUS1 hardly inhibited the cell colony formation ability of LO2 and WRL68 cells. (J, K) Knockdown of PUS1 hardly inhibited the cell proliferation of LO2 and WRL68 cells. (*P<0.05, **P<0.01, ***P<0.001, ****P<0.0001; ns, P>0.05).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Reverse Transcription Polymerase Chain Reaction, Expressing, Transfection, Control, MTT Assay, Knockdown, Apoptosis Assay

PUS1 promoted tumorigenesis and progression of HCC closely related to the mTOR and MYC pathways. (A) GSEA analysis between high and low PUS1 expression patients using hallmark gene sets based on TCGA–HCC database. (B–E) GSEA analysis revealed that MYC pathways, DNA repair, and MTORC1 pathways were significantly enriched in patients with high PUS1 expression. (F–H) The intersection analysis of the PUS1–dependent Ψ modification genes and MYC or MTORC1 pathway genes were applied. (I, J) RT–PCR analysis of PUS1 potential downstream targets in HepG2 cell after transfection with control or PUS1 siRNA. (**P<0.01, ***P<0.001).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: PUS1 promoted tumorigenesis and progression of HCC closely related to the mTOR and MYC pathways. (A) GSEA analysis between high and low PUS1 expression patients using hallmark gene sets based on TCGA–HCC database. (B–E) GSEA analysis revealed that MYC pathways, DNA repair, and MTORC1 pathways were significantly enriched in patients with high PUS1 expression. (F–H) The intersection analysis of the PUS1–dependent Ψ modification genes and MYC or MTORC1 pathway genes were applied. (I, J) RT–PCR analysis of PUS1 potential downstream targets in HepG2 cell after transfection with control or PUS1 siRNA. (**P<0.01, ***P<0.001).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Expressing, Modification, Reverse Transcription Polymerase Chain Reaction, Transfection, Control

PUS1 promotes cell proliferation depending on the mTOR and MYC pathways. (A, B) RT–PCR analysis of the mRNA expression of MYC, pre-MYC, mTOR and pre-mTOR in HCC cells after transfection with control or PUS1 siRNA. (C, D) WB testing of PUS1, MYC, mTOR, p-mTOR and P-S6 expression in HCC cells after transfection with control or PUS1 siRNA. (E-H) Cell proliferation of SNU449 and HepG2 cells transfected with PUS1 siRNA treatment with or without inhibitors of MYC (10058-F4, 10μM) or mTOR (rapamycin, 200nM) were analyzed by MTT assay. (**P<0.01, ***P<0.001, ****P<0.0001; ns, P>0.05).

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: PUS1 promotes cell proliferation depending on the mTOR and MYC pathways. (A, B) RT–PCR analysis of the mRNA expression of MYC, pre-MYC, mTOR and pre-mTOR in HCC cells after transfection with control or PUS1 siRNA. (C, D) WB testing of PUS1, MYC, mTOR, p-mTOR and P-S6 expression in HCC cells after transfection with control or PUS1 siRNA. (E-H) Cell proliferation of SNU449 and HepG2 cells transfected with PUS1 siRNA treatment with or without inhibitors of MYC (10058-F4, 10μM) or mTOR (rapamycin, 200nM) were analyzed by MTT assay. (**P<0.01, ***P<0.001, ****P<0.0001; ns, P>0.05).

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Reverse Transcription Polymerase Chain Reaction, Expressing, Transfection, Control, MTT Assay

A schematic view of PUS1 promoted tumorigenesis and progression of HCC dependent on the mTOR and MYC pathways.PUS1 expression was increased in HCC. However, knocking down PUS1 in HCC cells, the expression of MYC, p-mTOR and mTOR pathway‐related protein P-S6 were decreased. These results suggested that the role of PUS1 promoted tumorigenesis and progression of HCC is dependent on the mTOR and MYC pathways.

Journal: Frontiers in Oncology

Article Title: Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways

doi: 10.3389/fonc.2025.1576651

Figure Lengend Snippet: A schematic view of PUS1 promoted tumorigenesis and progression of HCC dependent on the mTOR and MYC pathways.PUS1 expression was increased in HCC. However, knocking down PUS1 in HCC cells, the expression of MYC, p-mTOR and mTOR pathway‐related protein P-S6 were decreased. These results suggested that the role of PUS1 promoted tumorigenesis and progression of HCC is dependent on the mTOR and MYC pathways.

Article Snippet: The immunohistochemistry (IHC) staining and subcellular localization analysis of PUS1 in HCC were obtained from THE HUMAN PROTEIN ATLAS ( https://www.proteinatlas.org/ ) TISSUE and PHATHOLOGY module.

Techniques: Expressing